Forward and Reverse Genetic Tools for Investigating Gene Function

Dharmesh Harwani

Maharaja Ganga Singh University, Bikaner-334001, Rajasthan, India

dharmesh_harwani@hotmail.com

+918764131240

Abstract: 

Genetics and molecular genomic approaches have been changed our perception towards biological processes. Reverse genetics describes the “gene to phenotype”approach, with which functions of a gene of interest can be examined by disrupting the gene expression at physiological level. Forward genetics is a “phenotype to gene” approach with which genes involved in a biological pathway can be identified through the screening of populations that contain random modifications throughout the genome, altering the gene function.

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